Search on: TELOMERIC REPEAT BINDING PROTEIN 1 
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Descriptor English:   Telomeric Repeat Binding Protein 1 
Descriptor Spanish:   Proteína 1 de Unión a Repeticiones Teloméricas 
Descriptor Portuguese:   Proteína 1 de Ligação a Repetições Teloméricas 
Synonyms English:   PIN2 Protein
TERF1 Protein
TTAGGG Repeat Binding Factor 1
TRF1 Protein  
Tree Number:   D12.776.260.735.750
D12.776.660.235.700.750
Definition English:   A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues. 
History Note English:   2003; for TRF1 PROTEIN use TELOMERE-BINDING PROTEINS (NM) 1997-2002; 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   37427 
Unique Identifier:   D035321 

Occurrence in VHL:
 

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